13 research outputs found

    Assessment of the Research Learning Needs of the University of Saskatchewan Librarians : A Case Study

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    As academic librarians with faculty status increasingly embrace research engagement as a core value and requirement, one of the little studied questions is the extent to which they possess the requisite knowledge and skills to conduct high quality research and scholarship, and what further learning needs they might have within the organizational setting. This paper summarizes an institutional case study of the research knowledge of academic librarians employed at the University of Saskatchewan, encompassing their current research interests, experiences, competencies, environmental context, and learning needs. The goal was to develop a framework for additional educational activities and institutional supports that would enhance their knowledge and skills

    Teaching Bibliometrics

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    The Censorship Phenomenon in College and Research Libraries: an Investigation of the Canadian Prairie Provinces, 1980-1985

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    National Core Library Statistics Program

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    CONTENTS Acknowledgments.................................................................................................iii Executive Summary ............................................................................................. iv Introduction ........................................................................................................... 1 Methodology .......................................................................................................... 3 1. Participating Libraries ....................................................................................................... 3 2. Survey Questions ................................................................................................................ 3 3. Collection of Data............................................................................................................... 4 4. Verification of Data.....................................................................................

    Tissue Selectivity of the Anabolic Steroid, 19-Nor-4-Androstenediol-3β,17β-Diol in Male Sprague Dawley Rats: Selective Stimulation of Muscle Mass and Bone Mineral Density Relative to Prostate Mass

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    Stimulation of prostate growth is a major concern with testosterone therapy in older hypogonadal men. As a result, nonsteroidal selective androgen receptor modulators with anabolic activity but less prostate stimulation are being developed. Anabolic steroids might exhibit similar tissue selectivity. We hypothesized the anabolic steroid 19-nor-4-androstenediol-3β,17β-diol (3β,19-NA) would increase muscle, lean body mass (LBM), and bone mineral density (BMD) with little stimulation of prostate growth. Male Sprague Dawley rats were implanted with SILASTIC brand (Dow Corning, Midland, MI) capsules containing 3β,19-NA (4, 8, or 16 cm), dihydrotestosterone (DHT) (8 cm), 19-nortestosterone (16 cm), or four empty capsules after undergoing either a sham operation (intact) or orchidectomy (ORX). Serum gonadotropins, measured after 4, 8, or 24 wk of treatment, were significantly lower in 3β,19-NA-treated vs. untreated, intact, and ORX rats (P < 0.05), and testosterone was lowered by 3β,19-NA-treatment of intact animals. LBM and BMD were assessed after 20 wk, and 4 wk later, rats were killed for levator ani muscle and prostate weights. Compared with ORX rats, 3β,19-NA-treated rats had dose-dependent higher levator ani muscle weights, LBM, and BMD, which were similar to intact and DHT-treated rats at the highest 3β,19-NA dose. In contrast, prostate weights in all 3β,19-NA-treated groups were similar to ORX rats and lower than intact and DHT- and 19-nortestosterone-treated rats even at the highest 3β,19-NA dose. In summary, 3β,19-NA increases muscle and bone mass without significant stimulation of prostate growth, suggesting it may have some properties of a steroidal selective androgen receptor modulator. Anabolic steroids such as 3β,19-NA should be studied further to determine their mechanisms of tissue selectivity and effects in men
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